263175-44-6

263175-44-6 structure

Name: Norverapamil-d7
Chemical Name: Norverapamil D7
CAS Number: 263175-44-6
Molecular Formula: C₂₆H₂₉D₇N₂O₄
Molecular Weight: 447.62
Catalog: Signaling Pathways Membrane Transporter/Ion Channel Calcium Channel
Create Date: 2020-01-23 19:03:51
Modify Date: 2024-01-12 19:57:22
Norverapamil D7 is a deuterium labeled Norverapamil ((±)-Norverapamil). Norverapamil, an N-demethylated metabolite of Verapamil, is a L-type calcium channel blocker and a P-glycoprotein (P-gp) function inhibitor[1][2].

Name	Norverapamil D7

Description	Norverapamil D7 is a deuterium labeled Norverapamil ((±)-Norverapamil). Norverapamil, an N-demethylated metabolite of Verapamil, is a L-type calcium channel blocker and a P-glycoprotein (P-gp) function inhibitor[1][2].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> Calcium Channel Research Areas >> Cardiovascular Disease Signaling Pathways >> Membrane Transporter/Ion Channel >> P-glycoprotein
References	[1]. Adams KN, et al. Verapamil, and its metabolite norverapamil, inhibit macrophage-induced, bacterial efflux pump-mediated tolerance to multiple anti-tubercular drugs. J Infect Dis. 2014 Aug 1;210(3):456-66. [2]. Pauli-Magnus C, et al. Characterization of the major metabolites of verapamil as substrates and inhibitors of P-glycoprotein. J Pharmacol Exp Ther. 2000 May;293(2):376-82.

Molecular Formula	C₂₆H₂₉D₇N₂O₄
Molecular Weight	447.62