CCT373566

Modify Date: 2025-08-26 10:44:44

CCT373566 Structure
CCT373566 structure
Common Name CCT373566
CAS Number 2378853-66-6 Molecular Weight 547.00
Density N/A Boiling Point N/A
Molecular Formula C26H29ClF2N6O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of CCT373566


CCT373566 is a potent and orally active degrader of transcriptional repressor BCL6, with an IC50 of 2.2 nM. CCT373566 shows strong antiproliferative efficacy in vitro and reduction in tumor growth in vivo[1].

 Names

Name CCT373566

 CCT373566 Biological Activity

Description CCT373566 is a potent and orally active degrader of transcriptional repressor BCL6, with an IC50 of 2.2 nM. CCT373566 shows strong antiproliferative efficacy in vitro and reduction in tumor growth in vivo[1].
Related Catalog
References

[1]. Huckvale R, et, al. Improved Binding Affinity and Pharmacokinetics Enable Sustained Degradation of BCL6 In Vivo. J Med Chem. 2022 Jun 23;65(12):8191-8207.

 Chemical & Physical Properties

Molecular Formula C26H29ClF2N6O3
Molecular Weight 547.00
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