Shanghai Nianxing Industrial Co., Ltd
China
Product Name: CCT373566
Price: Check
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: CCT373566
Price: ￥Inquiry/100mg ￥Inquiry/250mg ￥Inquiry/1g
Purity: 98.0%
Stocking Period: 10 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

2378853-66-6

2378853-66-6 structure

2378853-66-6 structure

Name: CCT373566
Chemical Name: CCT373566
CAS Number: 2378853-66-6
Molecular Formula: C₂₆H₂₉ClF₂N₆O₃
Molecular Weight: 547.00
Catalog: Signaling Pathways Apoptosis Bcl-2 Family
Create Date: 2022-08-16 15:40:17
Modify Date: 2025-08-26 10:44:44
CCT373566 is a potent and orally active degrader of transcriptional repressor BCL6, with an IC50 of 2.2 nM. CCT373566 shows strong antiproliferative efficacy in vitro and reduction in tumor growth in vivo[1].

Name	CCT373566

Description	CCT373566 is a potent and orally active degrader of transcriptional repressor BCL6, with an IC50 of 2.2 nM. CCT373566 shows strong antiproliferative efficacy in vitro and reduction in tumor growth in vivo[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Bcl-2 Family Research Areas >> Cancer
References	[1]. Huckvale R, et, al. Improved Binding Affinity and Pharmacokinetics Enable Sustained Degradation of BCL6 In Vivo. J Med Chem. 2022 Jun 23;65(12):8191-8207.

Molecular Formula	C₂₆H₂₉ClF₂N₆O₃
Molecular Weight	547.00

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