THP-PEG4-Pyrrolidine(N-Boc)-CH2OH

Modify Date: 2025-08-26 23:03:24

THP-PEG4-Pyrrolidine(N-Boc)-CH2OH structure	Common Name	THP-PEG4-Pyrrolidine(N-Boc)-CH2OH
	CAS Number	2378261-80-2	Molecular Weight	477.59
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₃H₄₃NO₉	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of THP-PEG4-Pyrrolidine(N-Boc)-CH2OH

THP-PEG4-Pyrrolidine(N-Boc)-CH2OH is a PEG-based PROTAC linker can be used in the synthesis of PROTAC K-Ras Degrader-1 (HY-129523)[1].

Name	THP-PEG4-Pyrrolidine(N-Boc)-CH2OH

Description	THP-PEG4-Pyrrolidine(N-Boc)-CH2OH is a PEG-based PROTAC linker can be used in the synthesis of PROTAC K-Ras Degrader-1 (HY-129523)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTAC K-Ras Degrader-1 is potent K-Ras degrader based PROTAC, exhibits ≥70% degradation efficacy in SW1573 cells[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
References	[1]. CREW, Andrew P., et al. MODULATORS OF PROTEOLYSIS AND ASSOCIATED METHODS OF USE. WO2019195609A2.

Molecular Formula	C₂₃H₄₃NO₉
Molecular Weight	477.59
Storage condition	-20°C

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: THP-PEG4-Pyrrolidine(N-Boc)-CH2OH
Price: Check
Purity: 95.0%
Delivery: 10 Day
Contact: Yang
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Price: ￥3500/100 mg

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