N-(Azido-PEG3)-N-Boc-PEG4-acid

Modify Date: 2024-01-12 10:57:58

N-(Azido-PEG3)-N-Boc-PEG4-acid Structure
N-(Azido-PEG3)-N-Boc-PEG4-acid structure
Common Name N-(Azido-PEG3)-N-Boc-PEG4-acid
CAS Number 2112731-95-8 Molecular Weight 566.64
Density N/A Boiling Point N/A
Molecular Formula C24H46N4O11 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of N-(Azido-PEG3)-N-Boc-PEG4-acid


N-(Azido-PEG3)-N-Boc-PEG4-acid is a PEG-based PROTAC linker with a terminal azide group and is used in the synthesis of PROTACs[1]

 Names

Name N-(Azido-PEG3)-N-Boc-PEG4-acid

 N-(Azido-PEG3)-N-Boc-PEG4-acid Biological Activity

Description N-(Azido-PEG3)-N-Boc-PEG4-acid is a PEG-based PROTAC linker with a terminal azide group and is used in the synthesis of PROTACs[1]
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
References

[1]. Kanazaki K, et al. Feasibility of poly(ethylene glycol) derivatives as diagnostic drug carriers for tumor imaging. J Control Release. 2016 Mar 28;226:115-23.

 Chemical & Physical Properties

Molecular Formula C24H46N4O11
Molecular Weight 566.64