Mc-1-f2

Modify Date: 2025-08-28 22:20:58

Mc-1-f2 Structure
Mc-1-f2 structure
Common Name Mc-1-f2
CAS Number 2376894-10-7 Molecular Weight 746.87
Density N/A Boiling Point N/A
Molecular Formula C37H46N16O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Mc-1-f2


MC-1-F2 is a FOXC2 inhibitor that reduces epithelial-mesenchymal transition (EMT) markers in breast cancer cells, suppresses cancer stem cell (CSC) properties and reduces invasiveness in castration-resistant prostate cancer (CRPC) cells. There is a synergistic effect between MC-1-F2 and Docetaxel, which has the potential to be used in combination to study CRPC[1].

 Names

Name MC-1-F2

 Mc-1-f2 Biological Activity

Description MC-1-F2 is a FOXC2 inhibitor that reduces epithelial-mesenchymal transition (EMT) markers in breast cancer cells, suppresses cancer stem cell (CSC) properties and reduces invasiveness in castration-resistant prostate cancer (CRPC) cells. There is a synergistic effect between MC-1-F2 and Docetaxel, which has the potential to be used in combination to study CRPC[1].
Related Catalog
Target

FOXC2[1].

References

[1]. Castaneda M, et al. A FOXC2 inhibitor, MC-1-F2, as a therapeutic candidate for targeting EMT in castration-resistant prostate cancer. Bioorg Med Chem Lett. 2023 Jul 15;91:129369.  

 Chemical & Physical Properties

Molecular Formula C37H46N16O2
Molecular Weight 746.87
InChIKey COSUURDQUHTOIY-UHFFFAOYSA-N
SMILES NC(N)=NCCCCNc1nc(Nc2ccc(Oc3ccccc3)cc2)nc(N2CCN(c3nc(N)nc(Nc4ccc(N5CCOCC5)cc4)n3)CC2)n1
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