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Mc-1-f2

Names

[ CAS No. ]:
2376894-10-7

[ Name ]:
Mc-1-f2

Biological Activity

[Description]:

MC-1-F2 is a FOXC2 inhibitor that reduces epithelial-mesenchymal transition (EMT) markers in breast cancer cells, suppresses cancer stem cell (CSC) properties and reduces invasiveness in castration-resistant prostate cancer (CRPC) cells. There is a synergistic effect between MC-1-F2 and Docetaxel, which has the potential to be used in combination to study CRPC[1].

[Related Catalog]:

Research Areas >> Cancer

[Target]

FOXC2[1].


[References]

[1]. Castaneda M, et al. A FOXC2 inhibitor, MC-1-F2, as a therapeutic candidate for targeting EMT in castration-resistant prostate cancer. Bioorg Med Chem Lett. 2023 Jul 15;91:129369.  

Chemical & Physical Properties

[ Molecular Formula ]:
C37H46N16O2

[ Molecular Weight ]:
746.87


Related Compounds

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