Scandenolide

Modify Date: 2025-08-25 18:32:01

Scandenolide Structure
Scandenolide structure
Common Name Scandenolide
CAS Number 23758-16-9 Molecular Weight 334.32
Density 1.38g/cm3 Boiling Point 584.4ºC at 760mmHg
Molecular Formula C17H18O7 Melting Point N/A
MSDS N/A Flash Point 260.4ºC

 Use of Scandenolide


Scandenolide is a sesquiterpene lactone that can be found in Philippines medicinal plant Mikania cordata. Scandenolide inhibits leukotriene and platelet activating factor synthesis in leukocytes[1][2].

 Names

Name Scandenolide
Synonym More Synonyms

 Scandenolide Biological Activity

Description Scandenolide is a sesquiterpene lactone that can be found in Philippines medicinal plant Mikania cordata. Scandenolide inhibits leukotriene and platelet activating factor synthesis in leukocytes[1][2].
Related Catalog
References

[1]. Ahmed M, et ,al. Analgesic sesquiterpene dilactone from Mikania cordata. Fitoterapia. 2001 Dec;72(8):919-21.  

[2]. Ysrael MC, et, al. Inhibition of leukotriene and platelet activating factor synthesis in leukocytes by the sesquiterpene lactone scandenolide. Planta Med. 1990 Jun;56(3):268-70.  

 Chemical & Physical Properties

Density 1.38g/cm3
Boiling Point 584.4ºC at 760mmHg
Molecular Formula C17H18O7
Molecular Weight 334.32
Flash Point 260.4ºC
Exact Mass 334.10500
PSA 91.43000
LogP 0.81900
Vapour Pressure 1.21E-13mmHg at 25°C
Index of Refraction 1.57

 Synonyms

5H-7,4-Methenofuro(3,2-c)oxireno(f)oxacycloundecin-5,9(7H)-dione,3-(acetyloxy)-1a,2,3,7a,8,10a,11,11a-octahydro-11a-methyl-8-methylene-,(1aS-(1aR*,3R*,7S*,7aS*,10aR*,11aR*))
Skandenolid
10a-methyl-3-methylidene-2,6-dioxodecahydro-4,7-(metheno)furo[3,2-c]oxireno[f]oxacycloundecin-8(6h)-yl acetate
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