P-CAB agent 1
Modify Date: 2025-08-28 18:03:10
P-CAB agent 1 structure
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Common Name | P-CAB agent 1 | ||
|---|---|---|---|---|
| CAS Number | 2374139-68-9 | Molecular Weight | 426.49 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C26H23FN4O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of P-CAB agent 1P-CAB agent 1 (compound B19) is a highly potent potassium-competitive acid blocker agent with an IC50 value of 60.50 nM for H+/K+-ATPase. P-CAB agent 1 has acceptable oral absorption in rats. P-CAB agent 1 can be used for researching acid-related disorders (ARDs)[1]. |
| Name | P-CAB agent 1 |
|---|
| Description | P-CAB agent 1 (compound B19) is a highly potent potassium-competitive acid blocker agent with an IC50 value of 60.50 nM for H+/K+-ATPase. P-CAB agent 1 has acceptable oral absorption in rats. P-CAB agent 1 can be used for researching acid-related disorders (ARDs)[1]. |
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| Related Catalog | |
| Target |
IC50: 60.50 nM (H+/K+-ATPase)[1] |
| In Vivo | P-CAB agent 1 has acceptable oral absorption in rats[1]. Pharmacokinetic Parameters of P-CAB agent 1 in female Sprague-Dawley rats[1]. IV (2 mg/kg) PO (8 mg/kg) AUC0-∞ (ug/L*hr) 519.57 341.49 t1/2 (ng/mL) 0.49 0.8 Cmax (ug/L) 149.93 17 F (%) 16.43 |
| References |
| Molecular Formula | C26H23FN4O |
|---|---|
| Molecular Weight | 426.49 |