ROS-generating agent 1

Modify Date: 2025-08-25 19:46:06

ROS-generating agent 1 structure	Common Name	ROS-generating agent 1
	CAS Number	2369030-41-9	Molecular Weight	411.34
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₁H₁₅F₆NO	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of ROS-generating agent 1

ROS-generating agent 1 (Compound 2c) covalently modifies the Sec-498 residue of TrxR to generate ROS. ROS-generating agent 1 reduces intracellular TrxR protein level. ROS-generating agent 1 results in ROS-dependent apoptosis and ferroptosis of NCI-H460 cells. ROS-generating agent 1 has anti-cancer activities[1].

Name	ROS-generating agent 1

Description	ROS-generating agent 1 (Compound 2c) covalently modifies the Sec-498 residue of TrxR to generate ROS. ROS-generating agent 1 reduces intracellular TrxR protein level. ROS-generating agent 1 results in ROS-dependent apoptosis and ferroptosis of NCI-H460 cells. ROS-generating agent 1 has anti-cancer activities[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer Signaling Pathways >> Apoptosis >> Ferroptosis
References	[1]. Liu X, et al. Tumor killing by a dietary curcumin mono-carbonyl analog that works as a selective ROS generator via TrxR inhibition. Eur J Med Chem. 2023 Mar 15;250:115191.

Molecular Formula	C₂₁H₁₅F₆NO
Molecular Weight	411.34

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: ROS-generating agent 1
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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.