Ponsegromab

Modify Date: 2025-09-13 06:01:52

Ponsegromab Structure
Ponsegromab structure
 Common Name Ponsegromab
CAS Number 2368950-15-4 Molecular Weight N/A
Density N/A Boiling Point N/A
Molecular Formula N/A Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Ponsegromab


Ponsegromab (PF 06946860) is a potent and selective humanized anti-GDF15 antibody inhibitor with anti-cachexia activity. Ponsegromab binds to GDF15 and prevents the binding of GDF15 to GFRAL, thereby blocking GDF15/GFRAL-mediated signaling. Ponsegromab can be used in the research of cancers[1][2].

 Names

Name Ponsegromab

 Ponsegromab Biological Activity

Description Ponsegromab (PF 06946860) is a potent and selective humanized anti-GDF15 antibody inhibitor with anti-cachexia activity. Ponsegromab binds to GDF15 and prevents the binding of GDF15 to GFRAL, thereby blocking GDF15/GFRAL-mediated signaling. Ponsegromab can be used in the research of cancers[1][2].
Related Catalog
Target

GDF15[1]

References

[1]. E.J. Roeland, et al. 1696TiP Phase Ib study to assess the effect of PF-06946860 on appetite following subcutaneous administration in patients with anorexia and advanced cancer. VOLUME 32, SUPPLEMENT 5, S1185, SEPTEMBER 01, 2021. Annals of oncology.

 Chemical & Physical Properties

No Any Chemical & Physical Properties
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Chemsrc provides Ponsegromab(CAS#:2368950-15-4) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of Ponsegromab are included as well.>> amp version: Ponsegromab

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