2-Chloro-6,7-dimethoxyquinazolin-4-amine

Modify Date: 2024-01-02 16:52:11

2-Chloro-6,7-dimethoxyquinazolin-4-amine Structure
2-Chloro-6,7-dimethoxyquinazolin-4-amine structure
Common Name 2-Chloro-6,7-dimethoxyquinazolin-4-amine
CAS Number 23680-84-4 Molecular Weight 239.658
Density 1.4±0.1 g/cm3 Boiling Point 374.0±42.0 °C at 760 mmHg
Molecular Formula C10H10ClN3O2 Melting Point 262-268 °C (dec.)(lit.)
MSDS Chinese USA Flash Point 180.0±27.9 °C
Symbol GHS07
GHS07
Signal Word Warning

 Names

Name 2-Chloro-4-amino-6,7-dimethoxyquinazoline
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 374.0±42.0 °C at 760 mmHg
Melting Point 262-268 °C (dec.)(lit.)
Molecular Formula C10H10ClN3O2
Molecular Weight 239.658
Flash Point 180.0±27.9 °C
Exact Mass 239.046158
PSA 70.26000
LogP 1.54
Vapour Pressure 0.0±0.8 mmHg at 25°C
Index of Refraction 1.649
Storage condition 2-8°C

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi:Irritant
Risk Phrases R36/37/38
Safety Phrases S26-S36-S37/39
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2933990090

 Synthetic Route

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles4

More Articles
Synthesis and biological profile of the enantiomers of [4-(4-amino-6,7-dimethoxyquinazolin-2-yl)-cis-octahydroquinoxalin- 1-yl]furan-2-ylmethanone (cyclazosin), a potent competitive alpha 1B- adrenoceptor antagonist.

J. Med. Chem. 39 , 4602, (1996)

The enantiomers of [4-(4-amino-6, 7-dimethoxyquinazolin-2-yl)-cis-octahydroquinoxalin-1-yl]-fu ran- 2-ylmethanone (cyclazosin, 1) were synthesized from the chiral furan-2-yl(cis-octahydroquinoxalin-1-...

2,4-Diamino-6,7-dimethoxyquinazolines. 3. 2-(4-Heterocyclylpiperazin-1-yl) derivatives as alpha 1-adrenoceptor antagonists and antihypertensive agents.

J. Med. Chem. 30(10) , 1794-8, (1987)

A series of 4-amino-6,7-dimethoxy-2(4-heterocyclylpiperazin-1-yl)quinazolines (3) was prepared and screened for alpha-adrenoceptor affinity and antihypertensive activity. These quinazoline derivatives...

2,4-Diamino-6,7-dimethoxyquinazolines. 2. 2-(4-Carbamoylpiperidino) derivatives as alpha 1-adrenoceptor antagonists and antihypertensive agents.

J. Med. Chem. 30(6) , 999-1003, (1987)

A series of 4-amino-2-(4-carbamoylpiperidino)-6,7-dimethoxyquinazolines (2) were synthesized and evaluated for alpha-adrenoceptor affinity and antihypertensive activity. These compounds displayed high...

 Synonyms

2-chloro-6,7-dimethoxy-4-aminoquinazoline
2-chloro-6,7-dimethoxyquinazolin-4-amine
EINECS 245-821-7
2-Chloro-4-amino-6,7-dimethoxyquinazoline
2-chlor-6,7-dimethoxychinazolin-4-amin
2-Chloro-4-AMino-6
7-DiMethoxy-Quinazoline
MFCD00051734
QUINAZOLINAMINE
4-Amino-2-Chloro-6,7-Dimethoxyquinoline
4-Amino-2-chloro-6,7-dimethoxyquinazoline
2-chloro-6,7-dimethoxy-4-quinazolinylamine
2-Chloro-6,7-dimethoxy-4-quinazolinamine
4-Quinazolinamine, 2-chloro-6,7-dimethoxy-
2-Chloro-4-amino-6,7-dimethoxy
2-Chloro-4-amino-6,7-dimetoxysynazaline
4-Amino-2-chloro-6,7-dimethoxy
2-Chloro-6,7-dimethoxy-4-quinazolinamine,4-Amino-2-chloro-6,7-dimethoxyquinazoline
2-chloro-4-amino-6,7-dimethoxy quinazoline