AD57 (hydrochloride)

Modify Date: 2025-08-25 11:02:01

AD57 (hydrochloride) Structure
AD57 (hydrochloride) structure
Common Name AD57 (hydrochloride)
CAS Number 2320261-72-9 Molecular Weight 491.897
Density N/A Boiling Point N/A
Molecular Formula C22H21ClF3N7O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of AD57 (hydrochloride)


AD57 hydrochloride is an orally active multikinase inhibitor, inhibits RET, BRAF, S6K and Src[1].

 Names

Name AD57 (hydrochloride)
Synonym More Synonyms

 AD57 (hydrochloride) Biological Activity

Description AD57 hydrochloride is an orally active multikinase inhibitor, inhibits RET, BRAF, S6K and Src[1].
Related Catalog
References

[1]. Dar AC, et al. Chemical genetic discovery of targets and anti-targets for cancer polypharmacology. Nature. 2012 Jun 6;486(7401):80-4.  

 Chemical & Physical Properties

Molecular Formula C22H21ClF3N7O
Molecular Weight 491.897
Exact Mass 491.144806

 Synonyms

1-[4-(4-Amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)phenyl]-3-[3-(trifluoromethyl)phenyl]urea hydrochloride (1:1)
AD57 (hydrochloride)
Urea, N-[4-[4-amino-1-(1-methylethyl)-1H-pyrazolo[3,4-d]pyrimidin-3-yl]phenyl]-N'-[3-(trifluoromethyl)phenyl]-, hydrochloride (1:1)
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