2320261-72-9

2320261-72-9 structure

Name: AD57 (hydrochloride)
Chemical Name: AD57 (hydrochloride)
CAS Number: 2320261-72-9
Molecular Formula: C₂₂H₂₁ClF₃N₇O
Molecular Weight: 491.897
Catalog: Signaling Pathways MAPK/ERK Pathway Raf
Create Date: 2021-08-10 12:02:34
Modify Date: 2025-08-25 11:02:01
AD57 hydrochloride is an orally active multikinase inhibitor, inhibits RET, BRAF, S6K and Src[1].

Name	AD57 (hydrochloride)
Synonyms	1-[4-(4-Amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)phenyl]-3-[3-(trifluoromethyl)phenyl]urea hydrochloride (1:1) AD57 (hydrochloride) Urea, N-[4-[4-amino-1-(1-methylethyl)-1H-pyrazolo[3,4-d]pyrimidin-3-yl]phenyl]-N'-[3-(trifluoromethyl)phenyl]-, hydrochloride (1:1)

Description	AD57 hydrochloride is an orally active multikinase inhibitor, inhibits RET, BRAF, S6K and Src[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Protein Tyrosine Kinase/RTK >> Src Signaling Pathways >> MAPK/ERK Pathway >> Raf Signaling Pathways >> MAPK/ERK Pathway >> Ribosomal S6 Kinase (RSK)
References	[1]. Dar AC, et al. Chemical genetic discovery of targets and anti-targets for cancer polypharmacology. Nature. 2012 Jun 6;486(7401):80-4.