NT-0796

Modify Date: 2025-08-25 08:19:09

NT-0796 Structure
NT-0796 structure
 Common Name NT-0796
CAS Number 2272917-13-0 Molecular Weight 409.48
Density N/A Boiling Point N/A
Molecular Formula C23H27N3O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of NT-0796


NT-0796 is a selective and CNS-penetrant NLRP3 inflammasome inhibitor with an IC50 of 0.32 nM in PBMC assay. NT-0796 is an isopropyl ester that undergoes intracellular conversion to NDT-19795, the carboxylic acid active species. NT-0796 has the potential for neuroinflammatory diseases research[1].

 Names

Name NT-0796

 NT-0796 Biological Activity

Description NT-0796 is a selective and CNS-penetrant NLRP3 inflammasome inhibitor with an IC50 of 0.32 nM in PBMC assay. NT-0796 is an isopropyl ester that undergoes intracellular conversion to NDT-19795, the carboxylic acid active species. NT-0796 has the potential for neuroinflammatory diseases research[1].
Related Catalog
References

[1]. David Harrison, et al. Discovery of Clinical Candidate NT-0796, a Brain-Penetrant and Highly Potent NLRP3 Inflammasome Inhibitor for Neuroinflammatory Disorders. J Med Chem. 2023 Oct 24.  

 Chemical & Physical Properties

Molecular Formula C23H27N3O4
Molecular Weight 409.48
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Chemsrc provides NT-0796(CAS#:2272917-13-0) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of NT-0796 are included as well.>> amp version: NT-0796

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