NT-0796

Modify Date: 2025-08-25 08:19:09

NT-0796 structure	Common Name	NT-0796
	CAS Number	2272917-13-0	Molecular Weight	409.48
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₃H₂₇N₃O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of NT-0796

NT-0796 is a selective and CNS-penetrant NLRP3 inflammasome inhibitor with an IC50 of 0.32 nM in PBMC assay. NT-0796 is an isopropyl ester that undergoes intracellular conversion to NDT-19795, the carboxylic acid active species. NT-0796 has the potential for neuroinflammatory diseases research[1].

Name	NT-0796

Description	NT-0796 is a selective and CNS-penetrant NLRP3 inflammasome inhibitor with an IC50 of 0.32 nM in PBMC assay. NT-0796 is an isopropyl ester that undergoes intracellular conversion to NDT-19795, the carboxylic acid active species. NT-0796 has the potential for neuroinflammatory diseases research[1].
Related Catalog	Signaling Pathways >> Immunology/Inflammation >> NOD-like Receptor (NLR) Research Areas >> Neurological Disease
References	[1]. David Harrison, et al. Discovery of Clinical Candidate NT-0796, a Brain-Penetrant and Highly Potent NLRP3 Inflammasome Inhibitor for Neuroinflammatory Disorders. J Med Chem. 2023 Oct 24.

Molecular Formula	C₂₃H₂₇N₃O₄
Molecular Weight	409.48
InChIKey	UMUQEMHROZVOTF-LJQANCHMSA-N
SMILES	CC(C)OC(=O)C(Cc1ncccn1)OC(=O)Nc1c2c(cc3c1CCC3)CCC2

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: NT-0796
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: NT-0796
Price: ￥550.0/5mg
Purity: 98.0%
Delivery: 10 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.