UBX1325

Modify Date: 2025-08-25 13:50:36

UBX1325 structure	Common Name	UBX1325
	CAS Number	2271269-01-1	Molecular Weight	1159.69
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₅₃H₅₉ClF₃N₆O₁₀PS₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of UBX1325

UBX1325 is an Bcl-xL inhibitor that promotes apoptosis in senescent cells. UBX1325 is a potent anti-aging agent that can be used in studies of age-related eye diseases such as diabetic macular oedema (DME), age-related macular degeneration (AMD) and diabetic retinopathy (DR)[1].

Name	UBX1325

Description	UBX1325 is an Bcl-xL inhibitor that promotes apoptosis in senescent cells. UBX1325 is a potent anti-aging agent that can be used in studies of age-related eye diseases such as diabetic macular oedema (DME), age-related macular degeneration (AMD) and diabetic retinopathy (DR)[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Bcl-2 Family Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Metabolic Disease
In Vitro	UBX1325 leads to a decrease in the anti-apoptotic Bcl-xL:Bim complex in retina by intravitreal (IVT) injection administration in oxygen induced retinopathy (OIR) C57BL/6 mice model[1]. UBX1325 can cause a decrease in retinal vascular permeability and promote retinal neovascularization in streptozotocin (STZ)-induced retinopathy mice model[1].
References	[1]. Pamela Tsuruda, et al. UBX1325, a small molecule inhibitor of Bcl-xL, attenuates vascular dysfunction in two animal models of retinopathy. Investigative Ophthalmology & Visual Science June 2021,Volume 62, Issue 8

Molecular Formula	C₅₃H₅₉ClF₃N₆O₁₀PS₃
Molecular Weight	1159.69
InChIKey	FSZILRQCEAUYPL-VQJSHJPSSA-N
SMILES	Cc1c(C(=O)O)c(-c2cccc(N3CCN(c4ccc(NS(=O)(=O)c5ccc(NC(CCN6CCC(OP(=O)(O)O)CC6)CSc6ccccc6)c(S(=O)(=O)C(F)(F)F)c5)cc4)CC3)c2)c(-c2ccc(Cl)cc2)n1C(C)C

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: UBX1325
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: UBX1325
Price: ￥Inquiry/100mg ￥Inquiry/250mg ￥Inquiry/1g
Purity: 98.0%
Delivery: 10 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.