Egfr-IN-7(TQB3804 )
Modify Date: 2025-08-24 07:18:29
Egfr-IN-7(TQB3804 ) structure
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Common Name | Egfr-IN-7(TQB3804 ) | ||
|---|---|---|---|---|
| CAS Number | 2267329-76-8 | Molecular Weight | 694.60 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C32H41BrN9O2P | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Egfr-IN-7(TQB3804 )EGFR-IN-7 (compound 34) is a selective and potent EGFR kinase inhibitor extracted from patent WO2019015655A1, has IC50s of 7.92 nM and 0.218 nM for EGFR (WT) and EGFR (mutant C797S/T790M/L858R) respectively, and shows anti-tumor activity[1]. |
| Name | EGFR-IN-7 |
|---|
| Description | EGFR-IN-7 (compound 34) is a selective and potent EGFR kinase inhibitor extracted from patent WO2019015655A1, has IC50s of 7.92 nM and 0.218 nM for EGFR (WT) and EGFR (mutant C797S/T790M/L858R) respectively, and shows anti-tumor activity[1]. |
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| Related Catalog | |
| Target |
EGFR (WT):7.92 nM (IC50) EGFR (C797S/T790M/L858R):0.218 nM (IC50) |
| References |
[1]. Aryl-phosphorus-oxygen compound as egfr kinase inhibitor. |
| Molecular Formula | C32H41BrN9O2P |
|---|---|
| Molecular Weight | 694.60 |
| InChIKey | ZYSKXRAGBGLELB-UHFFFAOYSA-N |
| SMILES | COc1cc(N2CCC(N3CCN(C)CC3)CC2)c(C)cc1Nc1ncc(Br)c(Nc2ccc3nccnc3c2P(C)(C)=O)n1 |