fosamprenavir

Modify Date: 2024-01-05 00:15:58

fosamprenavir Structure
fosamprenavir structure
Common Name fosamprenavir
CAS Number 226700-79-4 Molecular Weight 585.61
Density 1.4±0.1 g/cm3 Boiling Point N/A
Molecular Formula C25H36N3O9PS Melting Point N/A
MSDS N/A Flash Point N/A

 Use of fosamprenavir


Fosamprenavir (Amprenavir phosphate;GW 433908) is a phosphate ester prodrug of the antiretroviral protease inhibitor Amprenavir, with improved solubility[1]. Anti-HIV infection[1].

 Names

Name fosamprenavir
Synonym More Synonyms

 fosamprenavir Biological Activity

Description Fosamprenavir (Amprenavir phosphate;GW 433908) is a phosphate ester prodrug of the antiretroviral protease inhibitor Amprenavir, with improved solubility[1]. Anti-HIV infection[1].
Related Catalog
Target

HIV[1]

References

[1]. Falcoz C, et al. Pharmacokinetics of GW433908, a prodrug of amprenavir, in healthy male volunteers. J Clin Pharmacol. 2002 Aug;42(8):887-98.

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Molecular Formula C25H36N3O9PS
Molecular Weight 585.61
Exact Mass 585.190979
PSA 195.91000
LogP 3.36
Index of Refraction 1.612
Storage condition 2-8℃

 Synonyms

fosamprenavir
(3S)-Tetrahydro-3-furanyl [(2S,3R)-4-{[(4-aminophenyl)sulfonyl](isobutyl)amino}-1-phenyl-3-(phosphonooxy)-2-butanyl]carbamate
Lexiva
Amprenavir phosphate
((1S,2R)-3-(((4-Aminophenyl)sulfonyl)(2-methylpropyl)amino)-1-(phenylmethyl)-2-(phosphonooxy)propyl)carbamic Acid C-((3S)-Tetrahydro-3-furanyl) Ester
((3S)Oxolan-3-yloxy)-N-((1S,2R)-3-{[(4-aminophenyl)sulfonyl](2-methylpropyl)amino}-1-benzyl-2-(phosphonooxy)propyl)carboxamide
(3S)-Tetrahydrofuran-3-yl [(2S,3R)-4-{[(4-aminophenyl)sulfonyl](isobutyl)amino}-1-phenyl-3-(phosphonooxy)butan-2-yl]carbamate
GW 433 908
Carbamic acid, N-[(1S,2R)-3-[[(4-aminophenyl)sulfonyl](2-methylpropyl)amino]-1-(phenylmethyl)-2-(phosphonooxy)propyl]-, (3S)-tetrahydro-3-furanyl ester
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Price: ¥3221/10 mM * 1 mL in DMSO

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