1133702-41-6

1133702-41-6 structure

Name: Fosamprenavir-d4
Chemical Name: Fosamprenavir-d4
CAS Number: 1133702-41-6
Molecular Formula: C₂₅H₃₂D₄N₃O₉PS
Molecular Weight: 589.63
Catalog: Signaling Pathways Anti-infection HIV
Create Date: 2022-07-01 00:54:11
Modify Date: 2024-01-13 17:48:32
Fosamprenavir-d4 is deuterium labeled Fosamprenavir. Fosamprenavir (Amprenavir phosphate;GW 433908) is a phosphate ester prodrug of the antiretroviral protease inhibitor Amprenavir, with improved solubility[1]. Anti-HIV infection[1].

Name	Fosamprenavir-d4

Description	Fosamprenavir-d4 is deuterium labeled Fosamprenavir. Fosamprenavir (Amprenavir phosphate;GW 433908) is a phosphate ester prodrug of the antiretroviral protease inhibitor Amprenavir, with improved solubility[1]. Anti-HIV infection[1].
Related Catalog	Signaling Pathways >> Anti-infection >> HIV Research Areas >> Infection
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Falcoz C, et al. Pharmacokinetics of GW433908, a prodrug of amprenavir, in healthy male volunteers. J Clin Pharmacol. 2002 Aug;42(8):887-98.

Molecular Formula	C₂₅H₃₂D₄N₃O₉PS
Molecular Weight	589.63