PDE12-IN-1
Modify Date: 2024-01-11 16:49:34
PDE12-IN-1 structure
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Common Name | PDE12-IN-1 | ||
|---|---|---|---|---|
| CAS Number | 2259620-80-7 | Molecular Weight | 616.48 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C31H27BrFN5O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of PDE12-IN-1PDE12-IN-1 is a potent and selective PDE12 inhibitor with a pIC50 value for enzyme inhibition of 9.1. PDE12-IN-1 increases 2′,5′-linked adenylate polymers (2-5A) levels, and the pEC50 value is 7.7. PDE12-IN-1 shows antiviral activity[1]. |
| Name | PDE12-IN-1 |
|---|
| Description | PDE12-IN-1 is a potent and selective PDE12 inhibitor with a pIC50 value for enzyme inhibition of 9.1. PDE12-IN-1 increases 2′,5′-linked adenylate polymers (2-5A) levels, and the pEC50 value is 7.7. PDE12-IN-1 shows antiviral activity[1]. |
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| Related Catalog | |
| Target |
PDE12:9.1 (pIC50) |
| In Vitro | PDE12-IN-1 inhibits the EMCV-induced cytopathic effect in HeLa Ohio cells with a pIC50 of 6.7. PDE12-IN-1 inhibits HeLa Ohio cell proliferation in the absence of EMCV infection with a pIC50 of 5.7. PDE12-IN-1 inhibits the proliferation of both HeLa and HeLaΔPDE12 cells with a pIC50 of 5.7. PDE12-IN-1 inhibits HRV infection with a pIC50 of 6.9[1]. |
| References |
| Molecular Formula | C31H27BrFN5O3 |
|---|---|
| Molecular Weight | 616.48 |