JTP-117968

Modify Date: 2025-08-27 11:23:44

JTP-117968 Structure
JTP-117968 structure
Common Name JTP-117968
CAS Number 2250132-99-9 Molecular Weight 520.59
Density N/A Boiling Point N/A
Molecular Formula C31H31F3N2O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of JTP-117968


JTP-117968, a novel selective glucocorticoid receptor modulator (a non-steroidal SGRM, IC50 of 6.8 nM), exhibits improved transrepression/transactivation dissociation[1].

 Names

Name JTP-117968

 JTP-117968 Biological Activity

Description JTP-117968, a novel selective glucocorticoid receptor modulator (a non-steroidal SGRM, IC50 of 6.8 nM), exhibits improved transrepression/transactivation dissociation[1].
Related Catalog
In Vitro JTP-117968 has partial TR activity, but exhibits extremely low TA activity[1].
References

[1]. Takafumi Kurimoto, et al. JTP-117968, a novel selective glucocorticoid receptor modulator, exhibits improved transrepression/transactivation dissociation. Eur J Pharmacol. 2017 May 15;803:179-186.

 Chemical & Physical Properties

Molecular Formula C31H31F3N2O2
Molecular Weight 520.59
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