HP1328

Modify Date: 2025-08-27 16:53:47

HP1328 Structure
HP1328 structure
 Common Name HP1328
CAS Number 2245074-20-6 Molecular Weight 389.45
Density N/A Boiling Point N/A
Molecular Formula C23H23N3O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of HP1328


HP1328 is a potent inhibitor of FLT3 receptor tyrosine kinase (FLT3/ITD mutation). HP1328 is a benzoimidazole scaffold-based compound. HP1328 significantly reduces the leukemia burden and prolongs the survival of mice with FLT3/ITD leukemia[1].

 Names

Name HP1328

 HP1328 Biological Activity

Description HP1328 is a potent inhibitor of FLT3 receptor tyrosine kinase (FLT3/ITD mutation). HP1328 is a benzoimidazole scaffold-based compound. HP1328 significantly reduces the leukemia burden and prolongs the survival of mice with FLT3/ITD leukemia[1].
Related Catalog
References

[1]. Tian T, et al. Identification of the Benzoimidazole Compound as a Selective FLT3 Inhibitor by Cell-Based High-Throughput Screening of a Diversity Library. J Med Chem. 2022 Feb 24;65(4):3597-3605.

 Chemical & Physical Properties

Molecular Formula C23H23N3O3
Molecular Weight 389.45
InChIKey FNNZOQPZURDRII-UHFFFAOYSA-N
SMILES COc1cc(CNc2ccc3c(c2)ncn3-c2ccccc2)ccc1OCCO
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Chemsrc provides HP1328(CAS#:2245074-20-6) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of HP1328 are included as well.>> amp version: HP1328

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