ABN401

Modify Date: 2024-04-09 18:15:09

ABN401 Structure
ABN401 structure
Common Name ABN401
CAS Number 2242563-15-9 Molecular Weight 566.66
Density N/A Boiling Point N/A
Molecular Formula C29H34N12O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of ABN401


ABN401 is a highly potent and selective ATP-competitive c-MET inhibitor with an IC50 value of 10 nM. ABN401 has cytotoxic activity against MET-addicted cancer cells. ABN401 can inhibit c-MET phosphorylation in tumor tissues. ABN401 can be used for researching anticancer[1].

 Names

Name ABN401

 ABN401 Biological Activity

Description ABN401 is a highly potent and selective ATP-competitive c-MET inhibitor with an IC50 value of 10 nM. ABN401 has cytotoxic activity against MET-addicted cancer cells. ABN401 can inhibit c-MET phosphorylation in tumor tissues. ABN401 can be used for researching anticancer[1].
Related Catalog
Target

IC50: 10 nM (c-MET)[1]

References

[1]. Kim J, et al. Therapeutic Efficacy of ABN401, a Highly Potent and Selective MET Inhibitor, Based on Diagnostic Biomarker Test in MET-Addicted Cancer. Cancers (Basel). 2020;12(6):1575. Published 2020 Jun 15.

 Chemical & Physical Properties

Molecular Formula C29H34N12O
Molecular Weight 566.66
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