MEDS433

Modify Date: 2025-08-25 11:16:58

MEDS433 Structure
MEDS433 structure
Common Name MEDS433
CAS Number 2241027-61-0 Molecular Weight 401.321
Density N/A Boiling Point N/A
Molecular Formula C20H11F4N3O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of MEDS433


MEDS433 is a potent DHODH inhibitor with IC50 of 1.2 nM (hDHODH), inhibits in vitro replication of HSV-1 and HSV-2 in the nanomolar range.

 Names

Name MEDS433

 MEDS433 Biological Activity

Description MEDS433 is a potent DHODH inhibitor with IC50 of 1.2 nM (hDHODH), inhibits in vitro replication of HSV-1 and HSV-2 in the nanomolar range.
References 1. Luganini A, et al. Antiviral Res. 2021 May;189:105057. 2. Stefano Sainas, et al. J Med Chem. 2018 Jul 26;61(14):6034-6055.

 Chemical & Physical Properties

Molecular Formula C20H11F4N3O2
Molecular Weight 401.321
InChIKey JIIXZPWFDKPNKW-UHFFFAOYSA-N
SMILES O=C(Nc1c(F)c(F)c(-c2ccccc2)c(F)c1F)c1c(=O)[nH]n2ccccc12
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