MEDS433 structure
|
Common Name | MEDS433 | ||
|---|---|---|---|---|
| CAS Number | 2241027-61-0 | Molecular Weight | 401.321 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C20H11F4N3O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of MEDS433MEDS433 is a potent DHODH inhibitor with IC50 of 1.2 nM (hDHODH), inhibits in vitro replication of HSV-1 and HSV-2 in the nanomolar range. |
| Name | MEDS433 |
|---|
| Description | MEDS433 is a potent DHODH inhibitor with IC50 of 1.2 nM (hDHODH), inhibits in vitro replication of HSV-1 and HSV-2 in the nanomolar range. |
|---|---|
| References | 1. Luganini A, et al. Antiviral Res. 2021 May;189:105057. 2. Stefano Sainas, et al. J Med Chem. 2018 Jul 26;61(14):6034-6055. |
| Molecular Formula | C20H11F4N3O2 |
|---|---|
| Molecular Weight | 401.321 |
| InChIKey | JIIXZPWFDKPNKW-UHFFFAOYSA-N |
| SMILES | O=C(Nc1c(F)c(F)c(-c2ccccc2)c(F)c1F)c1c(=O)[nH]n2ccccc12 |