MEDS433
Names
[ CAS No. ]:
2241027-61-0
[ Name ]:
MEDS433
Biological Activity
[Description]:
MEDS433 is a potent DHODH inhibitor with IC50 of 1.2 nM (hDHODH), inhibits in vitro replication of HSV-1 and HSV-2 in the nanomolar range.
[References]
1. Luganini A, et al. Antiviral Res. 2021 May;189:105057. 2. Stefano Sainas, et al. J Med Chem. 2018 Jul 26;61(14):6034-6055.
Chemical & Physical Properties
[ Molecular Formula ]:
C20H11F4N3O2
[ Molecular Weight ]:
401.321