MEDS433

Names

[ Name ]:
MEDS433

Biological Activity

[Description]:

MEDS433 is a potent DHODH inhibitor with IC50 of 1.2 nM (hDHODH), inhibits in vitro replication of HSV-1 and HSV-2 in the nanomolar range.

[References]

1. Luganini A, et al. Antiviral Res. 2021 May;189:105057. 2. Stefano Sainas, et al. J Med Chem. 2018 Jul 26;61(14):6034-6055.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₀H₁₁F₄N₃O₂

[ Molecular Weight ]:
401.321

Related Compounds

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