EP1013
Modify Date: 2024-01-13 09:57:52
EP1013 structure
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Common Name | EP1013 | ||
|---|---|---|---|---|
| CAS Number | 223568-55-6 | Molecular Weight | 382.383 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 639.8±55.0 °C at 760 mmHg | |
| Molecular Formula | C18H23FN2O6 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 340.7±31.5 °C | |
Use of EP1013EP1013 is a broad-spectrum caspase selective inhibitor, used in the research of type 1 diabetes. |
| Name | EP1013 |
|---|---|
| Synonym | More Synonyms |
| Description | EP1013 is a broad-spectrum caspase selective inhibitor, used in the research of type 1 diabetes. |
|---|---|
| Related Catalog | |
| Target |
Caspase |
| In Vivo | EP1013 (1, 3, 10 mg/kg) significantly improves marginal islet mass function. Two animals in the 10 mg/kg EP1013 treatment group exhibit primary islet graft nonfunction, but the diabetes reversalrate for this group is not significantly different from the 3 mg/kg EP1013, 1 mg/kg EP1013, or 10 mg/kg zVAD groups. EP1013 therapy enhances functional syngeneic islet mass and promotes longevity of islet graft function[1]. |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 639.8±55.0 °C at 760 mmHg |
| Molecular Formula | C18H23FN2O6 |
| Molecular Weight | 382.383 |
| Flash Point | 340.7±31.5 °C |
| Exact Mass | 382.154022 |
| LogP | 2.88 |
| Vapour Pressure | 0.0±2.0 mmHg at 25°C |
| Index of Refraction | 1.523 |
| Storage condition | 2-8℃ |
| Pentanoic acid, 5-fluoro-3-[[(2S)-3-methyl-1-oxo-2-[[(phenylmethoxy)carbonyl]amino]butyl]amino]-4-oxo-, (3S)- |
| (3S)-3-({N-[(Benzyloxy)carbonyl]-L-valyl}amino)-5-fluoro-4-oxopentanoic acid |