TK4b

Modify Date: 2024-01-06 21:26:35

TK4b Structure
TK4b structure
Common Name TK4b
CAS Number 2232890-81-0 Molecular Weight 334.41
Density N/A Boiling Point N/A
Molecular Formula C21H22N2O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of TK4b


TK4b is a Janus kinase (JAK) inhibitor with the IC50 values of 19.40 nM and 18.42 nM for JAK2 and JAK3, respectively. TK4b can be used in lymphoid-derived diseases and leukemia cancer research[1].

 Names

Name TK4b

 TK4b Biological Activity

Description TK4b is a Janus kinase (JAK) inhibitor with the IC50 values of 19.40 nM and 18.42 nM for JAK2 and JAK3, respectively. TK4b can be used in lymphoid-derived diseases and leukemia cancer research[1].
Related Catalog
Target

JAK2:19.40 nM (IC50)

JAK3:18.42 nM (IC50)

References

[1]. Kamonpan Sanachai, et al. Pharmacophore-Based Virtual Screening and Experimental Validation of Pyrazolone-Derived Inhibitors toward Janus Kinases. ACS Omega 2022.

 Chemical & Physical Properties

Molecular Formula C21H22N2O2
Molecular Weight 334.41
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