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2232890-81-0

2232890-81-0 structure

2232890-81-0 structure

Name: TK4b
Chemical Name: TK4b
CAS Number: 2232890-81-0
Molecular Formula: C₂₁H₂₂N₂O₂
Molecular Weight: 334.41
Catalog: Signaling Pathways Epigenetics JAK
Create Date: 2022-10-20 18:25:02
Modify Date: 2024-01-06 21:26:35
TK4b is a Janus kinase (JAK) inhibitor with the IC50 values of 19.40 nM and 18.42 nM for JAK2 and JAK3, respectively. TK4b can be used in lymphoid-derived diseases and leukemia cancer research[1].

Name	TK4b

Description	TK4b is a Janus kinase (JAK) inhibitor with the IC50 values of 19.40 nM and 18.42 nM for JAK2 and JAK3, respectively. TK4b can be used in lymphoid-derived diseases and leukemia cancer research[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> JAK/STAT Signaling >> JAK Signaling Pathways >> Epigenetics >> JAK Signaling Pathways >> Stem Cell/Wnt >> JAK
Target	JAK2:19.40 nM (IC50) JAK3:18.42 nM (IC50)
References	[1]. Kamonpan Sanachai, et al. Pharmacophore-Based Virtual Screening and Experimental Validation of Pyrazolone-Derived Inhibitors toward Janus Kinases. ACS Omega 2022.

Molecular Formula	C₂₁H₂₂N₂O₂
Molecular Weight	334.41

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