IACS-9439

Modify Date: 2025-08-27 12:24:43

IACS-9439 Structure
IACS-9439 structure
Common Name IACS-9439
CAS Number 2231259-36-0 Molecular Weight 481.57
Density N/A Boiling Point N/A
Molecular Formula C23H27N7O3S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of IACS-9439


IACS-9439 is a potent, selective, and orally active CSF1R inhibitor with a Ki value of 1 nM inhibitor. IACS-9439 can be used for advanced solid tumors research[1].

 Names

Name IACS-9439

 IACS-9439 Biological Activity

Description IACS-9439 is a potent, selective, and orally active CSF1R inhibitor with a Ki value of 1 nM inhibitor. IACS-9439 can be used for advanced solid tumors research[1].
Related Catalog
References

[1]. Barbara Czako, et al. Discovery of IACS-9439, a Potent, Exquisitely Selective, and Orally Bioavailable Inhibitor of CSF1R. J Med Chem. 2020 Sep 10;63(17):9888-9911.  

 Chemical & Physical Properties

Molecular Formula C23H27N7O3S
Molecular Weight 481.57
InChIKey MUHWRSWKWURVPP-ROUUACIJSA-N
SMILES COc1cc(OCc2ccnc(Nc3cnn(C)c3)n2)cc2sc(NC3CCCCC3O)nc12
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