IACS-9439

Names

[ CAS No. ]:
2231259-36-0

[ Name ]:
IACS-9439

Biological Activity

[Description]:

IACS-9439 is a potent, selective, and orally active CSF1R inhibitor with a Ki value of 1 nM inhibitor. IACS-9439 can be used for advanced solid tumors research[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Protein Tyrosine Kinase/RTK >> c-Fms

[References]

[1]. Barbara Czako, et al. Discovery of IACS-9439, a Potent, Exquisitely Selective, and Orally Bioavailable Inhibitor of CSF1R. J Med Chem. 2020 Sep 10;63(17):9888-9911.  

Chemical & Physical Properties

[ Molecular Formula ]:
C23H27N7O3S

[ Molecular Weight ]:
481.57