AZ-3

Modify Date: 2024-01-10 19:00:43

Use of AZ-3

AZ-3 is a potent and selective JAK1 inhibitor with an IC50 of 34 nM.

Name	AZ-3

Description	AZ-3 is a potent and selective JAK1 inhibitor with an IC50 of 34 nM.
Related Catalog	Research Areas >> Cancer Signaling Pathways >> JAK/STAT Signaling >> JAK Signaling Pathways >> Epigenetics >> JAK Signaling Pathways >> Stem Cell/Wnt >> JAK
Target	IC50: 34 nM (JAK1)[1]
References	[1]. Grimster NP, et al. Discovery and Optimization of a Novel Series of Highly Selective JAK1 Kinase Inhibitors. J Med Chem. 2018 Jun 28;61(12):5235-5244.

Molecular Formula	C₂₀H₂₈FN₇
Molecular Weight	385.48