CJ-2360
Modify Date: 2024-01-11 18:55:25
CJ-2360 structure
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Common Name | CJ-2360 | ||
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| CAS Number | 2226742-61-4 | Molecular Weight | 475.56 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C27H30FN5O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of CJ-2360CJ-2360 is a potent and orally active ALK with IC50s of 2.2, 4.0, 8.8, 6.3, and 8.9 nM against wild-type ALK and F1197M, G1269A, L1196M, and S1206Y ALK mutants, respectively. CJ-2360 displays potenty activity against two clinically reported ALK mutants (C1156Y and L1196M) and a few other kinases (LTK, MERTK, CLK1, DAPK1, and DAPK2) among the 468 kinases evaluated. |
| Name | CJ-2360 |
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| Description | CJ-2360 is a potent and orally active ALK with IC50s of 2.2, 4.0, 8.8, 6.3, and 8.9 nM against wild-type ALK and F1197M, G1269A, L1196M, and S1206Y ALK mutants, respectively. CJ-2360 displays potenty activity against two clinically reported ALK mutants (C1156Y and L1196M) and a few other kinases (LTK, MERTK, CLK1, DAPK1, and DAPK2) among the 468 kinases evaluated. |
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| Molecular Formula | C27H30FN5O2 |
|---|---|
| Molecular Weight | 475.56 |