NBI-961

Modify Date: 2024-03-06 19:15:00

NBI-961 Structure
NBI-961 structure
Common Name NBI-961
CAS Number 2225902-98-5 Molecular Weight 568.61
Density N/A Boiling Point N/A
Molecular Formula C28H27F3N6O2S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of NBI-961


NBI-961 is a potent NEK2 inhibitor that inhibits proteasomal degradation. NBI-961 induces G2/mitosis arrest and apoptosis in diffuse large B cell lymphoma (DLBCL) cells[1].

 Names

Name NBI-961

 NBI-961 Biological Activity

Description NBI-961 is a potent NEK2 inhibitor that inhibits proteasomal degradation. NBI-961 induces G2/mitosis arrest and apoptosis in diffuse large B cell lymphoma (DLBCL) cells[1].
Related Catalog
References

[1]. Mason McCrury, et al. Bifunctional inhibitor reveals NEK2 as a therapeutic target and regulator of oncogenic pathways in lymphoma. Mol Cancer Ther. 2023 Oct 11.  

 Chemical & Physical Properties

Molecular Formula C28H27F3N6O2S
Molecular Weight 568.61