NBI-961

Names

[ Name ]:
NBI-961

Biological Activity

[Description]:

NBI-961 is a potent NEK2 inhibitor that inhibits proteasomal degradation. NBI-961 induces G2/mitosis arrest and apoptosis in diffuse large B cell lymphoma (DLBCL) cells[1].

[Related Catalog]:

Signaling Pathways >> Metabolic Enzyme/Protease >> Ser/Thr Protease

Signaling Pathways >> Apoptosis >> Apoptosis

Research Areas >> Cancer

[References]

[1]. Mason McCrury, et al. Bifunctional inhibitor reveals NEK2 as a therapeutic target and regulator of oncogenic pathways in lymphoma. Mol Cancer Ther. 2023 Oct 11.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₈H₂₇F₃N₆O₂S

[ Molecular Weight ]:
568.61

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.