Mofebutazone

Modify Date: 2025-08-25 18:55:35

Mofebutazone structure	Common Name	Mofebutazone
	CAS Number	2210-63-1	Molecular Weight	232.28
	Density	1.14g/cm3	Boiling Point	N/A
	Molecular Formula	C₁₃H₁₆N₂O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Mofebutazone

Mofebutazone, a monophenyl analogue of Phenylbutazone (DPB), is an anti-inflammatory compound. Mofebutazone can be used for research of asthma[1][2].

Name	mofebutazone
Synonym	More Synonyms

Description	Mofebutazone, a monophenyl analogue of Phenylbutazone (DPB), is an anti-inflammatory compound. Mofebutazone can be used for research of asthma[1][2].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
References	[1]. F.T. Delbeke, et al. Determination of mofebutazone and its 4-hydroxy metabolite in plasma and urine by high-performance liquid chromatography. Journal of Chromatography A. Volume 369, 1986, Pages 440-444 [2]. Khayyal MT,et al. Tolerability of mofebutazone in asthmatic patients. Int J Clin Pharmacol Res. 1995;15(4):145-51.

Description

Mofebutazone, a monophenyl analogue of Phenylbutazone (DPB), is an anti-inflammatory compound. Mofebutazone can be used for research of asthma[1][2].

Related Catalog

Signaling Pathways >> Others >> Others

Research Areas >> Inflammation/Immunology

References

[1]. F.T. Delbeke, et al. Determination of mofebutazone and its 4-hydroxy metabolite in plasma and urine by high-performance liquid chromatography. Journal of Chromatography A. Volume 369, 1986, Pages 440-444

[2]. Khayyal MT,et al. Tolerability of mofebutazone in asthmatic patients. Int J Clin Pharmacol Res. 1995;15(4):145-51.

Density	1.14g/cm3
Molecular Formula	C₁₃H₁₆N₂O₂
Molecular Weight	232.28
Exact Mass	232.12100
PSA	49.41000
LogP	2.26460
Index of Refraction	1.541

Mofebutazone MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UQ8420000

CHEMICAL NAME :: 3,5-Pyrazolidinedione, 4-butyl-1-phenyl-

CAS REGISTRY NUMBER :: 2210-63-1

BEILSTEIN REFERENCE NO. :: 0213056

LAST UPDATED :: 199612

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C13-H16-N2-O2

MOLECULAR WEIGHT :: 232.31

WISWESSER LINE NOTATION :: T5VMNV EHJ CR& E4

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1750 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PAHEAA Pharmaceutica Acta Helvetiae. (Schweizerische Apothekerzeitung, Postfach 3006, CH3000 Bern, 7, Switzerland) V.1- 1926- Volume(issue)/page/year: 39,155,1964

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 848 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia, Italy) V.8-43 1953-88 For publisher information, see FRMCE8 Volume(issue)/page/year: 14,347,1959

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 700 mg/kg

TOXIC EFFECTS :: Behavioral - tremor Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea

REFERENCE :: SCPHA4 Scientia Pharmaceutica. (Oesterreichische Apotheker-Verlagsgesellschaft MBH, Spitalgasse 31, 1094 Vienna 9, Austria) V.1- 1930- Volume(issue)/page/year: 37,185,1969

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 920 mg/kg

TOXIC EFFECTS :: Behavioral - tremor Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea

REFERENCE :: SCPHA4 Scientia Pharmaceutica. (Oesterreichische Apotheker-Verlagsgesellschaft MBH, Spitalgasse 31, 1094 Vienna 9, Austria) V.1- 1930- Volume(issue)/page/year: 37,185,1969

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 600 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. (Berlin, Ger.) V.110-253, 1925-66. For publisher information, see NSAPCC. Volume(issue)/page/year: 233,365,1958

HS Code	2933990090

Dimethyl butylm...

CAS#:39520-22-4

Phenylhydrazine

CAS#:100-63-0

Mofebutazone

CAS#:2210-63-1

Literature: US2790808 , ; Helvetica Chimica Acta, , vol. 36, p. 75,79, 81

Phenylhydrazine

CAS#:100-63-0

Diethyl 2-butyl...

CAS#:133-08-4

Mofebutazone

CAS#:2210-63-1

Literature: Canadian Journal of Research, Section B: Chemical Sciences, , vol. 28, p. 720,725 Australian Journal of Chemistry, , vol. 27, p. 2447,2448

Precursor 3
CAS#:39520-22-4 Dimethyl butylm... CAS#:100-63-0 Phenylhydrazine CAS#:133-08-4 Diethyl 2-butyl...
DownStream 1
CAS#:55228-09-6 4-hydroxymofebu...

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 3,5-Pyrazolidinedione,4-butyl-1-phenyl-
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

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