ML211
Modify Date: 2024-01-05 08:39:46
ML211 structure
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Common Name | ML211 | ||
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| CAS Number | 2205032-89-7 | Molecular Weight | 418.531 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 583.9±42.0 °C at 760 mmHg | |
| Molecular Formula | C25H30N4O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 306.9±27.9 °C | |
Use of ML211ML-211 is a carbamate-based dual inhibitor of acyl-protein thioesterase 1 (APT1)/lysophospholipase 1 (LYPLA1) (IC50=17 nM) and LYPLA2 (IC50=30 nM). ML-211 also inhibits theserine hydrolase ABHD11 with an IC50 value of 10 nM but is ≥ 50-fold selective for LYPLA in a panel of 20 additional serine hydrolases[1]. |
| Name | ML-211 |
|---|---|
| Synonym | More Synonyms |
| Description | ML-211 is a carbamate-based dual inhibitor of acyl-protein thioesterase 1 (APT1)/lysophospholipase 1 (LYPLA1) (IC50=17 nM) and LYPLA2 (IC50=30 nM). ML-211 also inhibits theserine hydrolase ABHD11 with an IC50 value of 10 nM but is ≥ 50-fold selective for LYPLA in a panel of 20 additional serine hydrolases[1]. |
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| Related Catalog | |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 583.9±42.0 °C at 760 mmHg |
| Molecular Formula | C25H30N4O2 |
| Molecular Weight | 418.531 |
| Flash Point | 306.9±27.9 °C |
| Exact Mass | 418.236877 |
| LogP | 3.87 |
| Vapour Pressure | 0.0±1.7 mmHg at 25°C |
| Index of Refraction | 1.616 |
| {4-[Hydroxy(diphenyl)methyl]-2H-1,2,3-triazol-2-yl}[4-(2-methyl-2-propanyl)-1-piperidinyl]methanone |
| Methanone, [4-(1,1-dimethylethyl)-1-piperidinyl][4-(hydroxydiphenylmethyl)-2H-1,2,3-triazol-2-yl]- |
| ML-211 |