Selamectin

Modify Date: 2024-01-01 22:53:59

Selamectin structure	Common Name	Selamectin
	CAS Number	220119-17-5	Molecular Weight	769.960
	Density	1.4±0.1 g/cm3	Boiling Point	917.0±65.0 °C at 760 mmHg
	Molecular Formula	C₄₃H₆₃NO₁₁	Melting Point	N/A
	MSDS	USA	Flash Point	508.4±34.3 °C

Use of Selamectin

Selamectin is an anthelminthic which can be used on dogs and cats.

Name	Selamectin
Synonym	More Synonyms

Description	Selamectin is an anthelminthic which can be used on dogs and cats.
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Infection
In Vivo	Three monthly treatments with Selamectin/sarolaner provide high and consistent efficacy against I. ricinus for the entire duration of the study period. The percentage efficacy against I. ricinus is numerically higher in the Selemectin/sarolaner treating group than in the fluralaner-treating group on Days 56, 84 and 91[1]. All dogs are tested negative by both tests after receiving topical treatment with Selamectin monthly for 36 months[2].
Animal Admin	The cats are weighed on Days-2, 29 and 58 to calculate the dosing. Cats in group 1 (control group) remain untreated. On Day 0, the cats in group 3 are treated with fluralaner at the minimum recommending label dose of 40.0 mg per kg body weight. On Days 0, 30 and 60, the cats in group 2 are treated with the new spot-on formulation at the minimum recommending label dose of 1.0 mg/kg sarolaner and 6.0 mg/kg Selamectin. The cats are observed at different time points after treatment for possible adverse reactions to treatment. On Day 0, administration site observations are performed on all cats 30 min (±5 min), 3 h (±15 min) and 24 h (±1 h) and again on Days 3 and 5 after treatment[1].
References	[1]. Thomas Geurden, et al. Comparative efficacy of a new spot-on combination product containing selamectin and sarolaner (Stronghold®Plus) versus fluralaner (Bravecto®) against induced infestations with Ixodes ricinus ticks on cats. Published online 2017 Jun 29. [2]. Maria de Fátima Chicarino Varajao Moraes-da-Silva, et al. Selamectin for the prevention of canine Dirofilaria immitis infection: field efficacy in client-owned dogs in a high risk area. Published online 2016 Jul 22.

Density	1.4±0.1 g/cm3
Boiling Point	917.0±65.0 °C at 760 mmHg
Molecular Formula	C₄₃H₆₃NO₁₁
Molecular Weight	769.960
Flash Point	508.4±34.3 °C
Exact Mass	769.440125
PSA	154.73000
LogP	6.83
Vapour Pressure	0.0±0.6 mmHg at 25°C
Index of Refraction	1.618
Storage condition	2-8°C

RIDADR	NONH for all modes of transport

Determination of avermectins: a QuEChERS approach to the analysis of food samples.

Food Chem. 181 , 57-63, (2015)

We present a simple method for extracting avermectines from meat, based on a QuEChERS approach followed by liquid chromatography (LC) coupled to triple quadrupole (QqQ) tandem mass spectrometry (MS/MS...

The river blindness drug Ivermectin and related macrocyclic lactones inhibit WNT-TCF pathway responses in human cancer.

EMBO Mol. Med. 6(10) , 1263-78, (2014)

Constitutive activation of canonical WNT-TCF signaling is implicated in multiple diseases, including intestine and lung cancers, but there are no WNT-TCF antagonists in clinical use. We have performed...

(2aE,4E,5'S,6S,6'S,7S,8E,11R,13R,15S,17aR,20Z,20aR,20bS)-6'-cyclohexyl-20b-hydroxy-20-(hydroxyimino)-5',6,8,19-tetramethyl-17-oxo-3',4',5',6,6',10,11,14,15,17,17a,20,20a,20b-tetradecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-3-O-methyl-α-L-arabino-hexopyranoside

(1'R,2R,4'S,5S,6S,8'R,10'E,12'S,13'S,14'E,16'E,20'R,21'Z,24'S)-6-Cyclohexyl-24'-hydroxy-21'-(hydroxyimino)-5,11',13',22'-tetramethyl-2'-oxo-3,4,5,6-tetrahydrospiro[pyran-2,6'-[3,7,19]trioxatetracyclo[ ;15.6.1.1.0]pentacosa[10,14,16,22]tetraen]-12'-yl 2,6-dideoxy-3-O-methyl-α-L-arabino-hexopyranoside

hypnocarpic acid

(1'R,2R,4'S,5S,6S,8'R,10'E,12'S,13'S,14'E,16'E,20'R,21'Z,24'S)-6-Cyclohexyl-24'-hydroxy-21'-(hydroxyimino)-5,11',13',22'-tetramethyl-2'-oxo-3,4,5,6-tetrahydrospiro[pyran-2,6'-[3,7,19]trioxatetracyclo[15.6.1.1.0]pentacosa[10,14,16,22]tetraen]-12'-yl-2,6-dideoxy-3-O-methyl-α-L-arabino-hexopyranoside

(1'R,2R,4'S,5S,6S,8'R,10'E,12'S,13'S,14'E,16'E,20'R,21'Z,24'S)-6-Cyclohexyl-24'-hydroxy-21'-(hydroxyimino)-5,11',13',22'-tetramethyl-2'-oxo-3,4,5,6-tetrahydrospiro[pyran-2,6'-[3,7,19]trioxatetracyclo[15.6.1.1.0]pentacosa[10,14,16,22]tetraen]-12'-yl 2,6-dideoxy-3-O-methyl-α-L-arabino-hexopyranoside

Stronghold

Selamectin

Revolution

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Selamectin
Price: ￥906.0/250mg ￥2266.0/1g ￥6806.0/5g
Purity: 95.0%
Stocking Period: 2 Day
Contact: Liu jia

DC Chemicals Limited
China
Product Name: Selamectin
Price: $450.0/100mg $700.0/250mg $1300.0/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Zhejiang Hangyu API Co., Ltd
China
Product Name: Selamectin
Price: ￥Inquiry/1kg
Purity: 99.5%
Stocking Period: Inquiry
Contact: Vinnie

Henan Tianfu Chemical Co., Ltd.
China
Product Name: Selamectin
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Stocking Period: Inquiry
Contact: Anson

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Selamectin

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