NLX-204
Modify Date: 2024-04-05 20:37:03
NLX-204 structure
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Common Name | NLX-204 | ||
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| CAS Number | 2170405-10-2 | Molecular Weight | 409.862 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C20H22ClF2N3O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of NLX-204NLX-204 (NLX204) is a potent, selective, ERK1/2 phosphorylation-preferring serotonin 5 HT1A receptor agonist with pEC50 of 9.37; shows promising pharmacokinetic profile, also robustly stimulates ERK1/2 phosphorylation in rat cortex and showed highly potent (MED=0.16 mg/kg) and efficacious antidepressant-like activity, totally eliminating immobility in the rat Porsolt test. |
| Name | NLX-204 |
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| Description | NLX-204 (NLX204) is a potent, selective, ERK1/2 phosphorylation-preferring serotonin 5 HT1A receptor agonist with pEC50 of 9.37; shows promising pharmacokinetic profile, also robustly stimulates ERK1/2 phosphorylation in rat cortex and showed highly potent (MED=0.16 mg/kg) and efficacious antidepressant-like activity, totally eliminating immobility in the rat Porsolt test. |
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| References | References 1. Sniecikowska J, et al. J Med Chem. 2019 Feb 5. doi: 10.1021/acs.jmedchem.9b00062. View Related Products by Target Histamine Receptor |
| Molecular Formula | C20H22ClF2N3O2 |
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| Molecular Weight | 409.862 |