AR-C 118925XX
Modify Date: 2025-08-25 20:58:04
AR-C 118925XX structure
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Common Name | AR-C 118925XX | ||
|---|---|---|---|---|
| CAS Number | 216657-60-2 | Molecular Weight | 537.592 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C28H23N7O3S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of AR-C 118925XXAR-C118925XX is a selective P2Y2 receptor antagonist. AR-C118925XX inhibits ATP-induced IL-6 production and phosphorylation of p38. AR-C118925XX also inhibits Bleomycin (HY-108345)-induced dermal fibrosis in mice. AR-C118925XX also inhibits ATP-induced tumor growth[1][2]. |
| Name | AR-C118925XX |
|---|---|
| Synonym | More Synonyms |
| Description | AR-C118925XX is a selective P2Y2 receptor antagonist. AR-C118925XX inhibits ATP-induced IL-6 production and phosphorylation of p38. AR-C118925XX also inhibits Bleomycin (HY-108345)-induced dermal fibrosis in mice. AR-C118925XX also inhibits ATP-induced tumor growth[1][2]. |
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| Related Catalog | |
| Target |
P2Y2 Receptor |
| In Vivo | AR-C118925XX (i.p.) 抑制 Bleomycin 对小鼠真皮厚度的增加[1]。 |
| References |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Molecular Formula | C28H23N7O3S |
| Molecular Weight | 537.592 |
| Exact Mass | 537.158325 |
| LogP | 4.78 |
| Index of Refraction | 1.756 |
| InChIKey | PVKNPGQAFNALOI-UHFFFAOYSA-N |
| SMILES | Cc1ccc2c(c1)C=Cc1cc(C)ccc1C2c1cn(Cc2ccc(C(=O)Nc3nn[nH]n3)o2)c(=O)[nH]c1=S |
| AR-C118925XX |
| 2-Furancarboxamide, 5-[[5-(2,8-dimethyl-5H-dibenzo[a,d]cyclohepten-5-yl)-3,4-dihydro-2-oxo-4-thioxo-1(2H)-pyrimidinyl]methyl]-N-1H-tetrazol-5-yl- |
| 5-{[5-(2,8-Dimethyl-5H-dibenzo[a,d][7]annulen-5-yl)-2-oxo-4-thioxo-3,4-dihydro-1(2H)-pyrimidinyl]methyl}-N-(1H-tetrazol-5-yl)-2-furamide |