5-Chloro-2-furaldehyde

Modify Date: 2024-01-09 15:54:29

5-Chloro-2-furaldehyde Structure
5-Chloro-2-furaldehyde structure
Common Name 5-Chloro-2-furaldehyde
CAS Number 21508-19-0 Molecular Weight 130.529
Density 1.4±0.1 g/cm3 Boiling Point 190.0±20.0 °C at 760 mmHg
Molecular Formula C5H3ClO2 Melting Point 34-37ºC(lit.)
MSDS Chinese USA Flash Point 68.7±21.8 °C
Symbol GHS07
GHS07
Signal Word Warning

 Names

Name 5-chlorofuran-2-carbaldehyde
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 190.0±20.0 °C at 760 mmHg
Melting Point 34-37ºC(lit.)
Molecular Formula C5H3ClO2
Molecular Weight 130.529
Flash Point 68.7±21.8 °C
Exact Mass 129.982162
PSA 30.21000
LogP 1.50
Vapour Pressure 0.6±0.4 mmHg at 25°C
Index of Refraction 1.543
Storage condition 2-8°C
Water Solubility Insoluble in water.

 MSDS


Section1. IDENTIFICATION OF THE SUBSTANCE/MIXTURE
Product identifiers
Product name: 5-Chloro-2-furaldehyde
CAS-No.: 21508-19-0


Section2. HAZARDS IDENTIFICATION
Classification of the substance or mixture
Classification according to Regulation (EC) No 1272/2008 [EU-GHS/CLP]
Skin irritation (Category 2)
Eye irritation (Category 2)
Specific target organ toxicity - single exposure (Category 3)
Classification according to EU Directives 67/548/EEC or 1999/45/EC
Irritating to eyes, respiratory system and skin.
Label elements
Labelling according Regulation (EC) No 1272/2008 [CLP]
Pictogram
Signal wordWarning
Hazard statement(s)
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
Precautionary statement(s)
Avoid breathing dust/ fume/ gas/ mist/ vapours/ spray.
P305 + P351 + P338IF IN EYES: Rinse cautiously with water for several minutes. Remove
contact lenses, if present and easy to do. Continue rinsing.
Supplemental Hazardnone
Statements
According to European Directive 67/548/EEC as amended.
Hazard symbol(s)
R-phrase(s)
R36/37/38Irritating to eyes, respiratory system and skin.
S-phrase(s)
S26In case of contact with eyes, rinse immediately with plenty of water and
seek medical advice.
S36Wear suitable protective clothing.
Other hazards - none

Section3. COMPOSITION/INFORMATION ON INGREDIENTS
Substances
Formula: C5H3ClO2
Molecular Weight: 130,53 g/mol
ComponentConcentration
5-Chloro-2-furaldehyde
CAS-No.21508-19-0-

Section4. FIRST AID MEASURES
Description of first aid measures
General advice
Consult a physician. Show this safety data sheet to the doctor in attendance.
If inhaled
If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
In case of skin contact
Wash off with soap and plenty of water. Consult a physician.
In case of eye contact
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
If swallowed
Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.
Most important symptoms and effects, both acute and delayed
To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly
investigated.
Indication of any immediate medical attention and special treatment needed
no data available

Section5. FIRE-FIGHTING MEASURES
Extinguishing media
Suitable extinguishing media
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Hydrogen chloride gas
Advice for firefighters
Wear self contained breathing apparatus for fire fighting if necessary.
Further information
no data available

Section6. ACCIDENTAL RELEASE MEASURES
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment. Avoid dust formation. Avoid breathing vapors, mist or gas. Ensure
adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust.
Environmental precautions
Do not let product enter drains.
Methods and materials for containment and cleaning up
Pick up and arrange disposal without creating dust. Sweep up and shovel. Keep in suitable, closed
containers for disposal.
Reference to other sections
For disposal see section 13.

Section7. HANDLING AND STORAGE
Precautions for safe handling
Avoid contact with skin and eyes. Avoid formation of dust and aerosols.
Provide appropriate exhaust ventilation at places where dust is formed.Normal measures for preventive fire
protection.
Conditions for safe storage, including any incompatibilities
Store in cool place. Keep container tightly closed in a dry and well-ventilated place.
Recommended storage temperature: 2 - 8 °C
Specific end uses
no data available

Section8. EXPOSURE CONTROLS/PERSONAL PROTECTION
Control parameters
Components with workplace control parameters
Exposure controls
Appropriate engineering controls
Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at
the end of workday.
Personal protective equipment
Eye/face protection
Safety glasses with side-shields conforming to EN166 Use equipment for eye protection tested and
approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Skin protection
Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique
(without touching glove's outer surface) to avoid skin contact with this product. Dispose of
contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.
The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the
standard EN 374 derived from it.
Body Protection
impervious clothing, The type of protective equipment must be selected according to the
concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection
For nuisance exposures use type P95 (US) or type P1 (EU EN 143) particle respirator.For higher
level protection use type OV/AG/P99 (US) or type ABEK-P2 (EU EN 143) respirator cartridges. Use
respirators and components tested and approved under appropriate government standards such as
NIOSH (US) or CEN (EU).

Section9. PHYSICAL AND CHEMICAL PROPERTIES
Information on basic physical and chemical properties
a) AppearanceForm: crystalline
Colour: light yellow
b) Odourno data available
c) Odour Thresholdno data available
d) pHno data available
e) Melting point/freezingMelting point/range: 34 - 37 °C - lit.
point
f) Initial boiling point and 70 °C at 13 hPa
boiling range
g) Flash pointno data available
h) Evaporation rateno data available
i) Flammability (solid, gas) no data available
j) Upper/lowerno data available
flammability or
explosive limits
k) Vapour pressureno data available
l) Vapour densityno data available
m) Relative densityno data available
n) Water solubilityno data available
o) Partition coefficient: n- no data available
octanol/water
p) Autoignitionno data available
temperature
q) Decompositionno data available
temperature
r) Viscosityno data available
s) Explosive propertiesno data available
t) Oxidizing propertiesno data available
Other safety information
no data available

Section10. STABILITY AND REACTIVITY
Reactivity
no data available
Chemical stability
no data available
Possibility of hazardous reactions
no data available
Conditions to avoid
no data available
Incompatible materials
Strong oxidizing agents
Hazardous decomposition products
Other decomposition products - no data available

Section11. TOXICOLOGICAL INFORMATION
Information on toxicological effects
Acute toxicity
no data available
Skin corrosion/irritation
no data available
Serious eye damage/eye irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
IARC:No component of this product present at levels greater than or equal to 0.1% is identified as
probable, possible or confirmed human carcinogen by IARC.
Reproductive toxicity
no data available
Specific target organ toxicity - single exposure
Inhalation - May cause respiratory irritation.
Specific target organ toxicity - repeated exposure
no data available
Aspiration hazard
no data available
Potential health effects
InhalationMay be harmful if inhaled. Causes respiratory tract irritation.
IngestionMay be harmful if swallowed.
SkinMay be harmful if absorbed through skin. Causes skin irritation.
EyesCauses serious eye irritation.
Signs and Symptoms of Exposure
To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly
investigated.
Additional Information
RTECS: Not available

Section12. ECOLOGICAL INFORMATION
Toxicity
no data available
Persistence and degradability
no data available
Bioaccumulative potential
no data available
Mobility in soil
no data available
Results of PBT and vPvB assessment
no data available
Other adverse effects
no data available

Section13. DISPOSAL CONSIDERATIONS
Waste treatment methods
Product
Offer surplus and non-recyclable solutions to a licensed disposal company. Contact a licensed professional
waste disposal service to dispose of this material. Dissolve or mix the material with a combustible solvent
and burn in a chemical incinerator equipped with an afterburner and scrubber.
Contaminated packaging
Dispose of as unused product.

Section14. TRANSPORT INFORMATION
UN number
ADR/RID: -IMDG: -IATA: -
UN proper shipping name
ADR/RID: Not dangerous goods
IMDG: Not dangerous goods
IATA:Not dangerous goods
Transport hazard class(es)
ADR/RID: -IMDG: -IATA: -
Packaging group
ADR/RID: -IMDG: -IATA: -
Environmental hazards
ADR/RID: noIMDG Marine pollutant: noIATA: no
Special precautions for user
no data available

Section15. REGULATORY INFORMATION
This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006.
Safety, health and environmental regulations/legislation specific for the substance or mixture
no data available
Chemical Safety Assessment


SECTION 16 - ADDITIONAL INFORMATION
N/A

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi: Irritant;
Risk Phrases 36/37/38
Safety Phrases 26-36
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2932190090

 Synthetic Route

~53%

5-Chloro-2-furaldehyde Structure

5-Chloro-2-fura...

CAS#:21508-19-0

Literature: WO2004/33440 A1, ; Page 238 ; WO 2004/033440 A1

~92%

5-Chloro-2-furaldehyde Structure

5-Chloro-2-fura...

CAS#:21508-19-0

Literature: Australian Journal of Chemistry, , vol. 63, # 12 p. 1619 - 1626

~34%

5-Chloro-2-furaldehyde Structure

5-Chloro-2-fura...

CAS#:21508-19-0

Literature: Synthesis, , # 3 p. 248 - 250

~%

5-Chloro-2-furaldehyde Structure

5-Chloro-2-fura...

CAS#:21508-19-0

Literature: Nippon Kagaku Zasshi, , vol. 79, p. 1366,1369 Chem.Abstr., , p. 24633

~%

5-Chloro-2-furaldehyde Structure

5-Chloro-2-fura...

CAS#:21508-19-0

Literature: Journal of Organic Chemistry, , vol. 10, p. 541

~%

5-Chloro-2-furaldehyde Structure

5-Chloro-2-fura...

CAS#:21508-19-0

Literature: Recueil des Travaux Chimiques des Pays-Bas, , vol. 50, p. 833,835

~%

5-Chloro-2-furaldehyde Structure

5-Chloro-2-fura...

CAS#:21508-19-0

Literature: Nippon Kagaku Zasshi, , vol. 79, p. 1366,1369 Chem.Abstr., , p. 24633

~%

5-Chloro-2-furaldehyde Structure

5-Chloro-2-fura...

CAS#:21508-19-0

Literature: Recueil des Travaux Chimiques des Pays-Bas, , vol. 50, p. 833,835

 Customs

HS Code 2932190090
Summary 2932190090 other compounds containing an unfused furan ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

 Articles5

More Articles
The Reaction of Certain Substituted Furfurals with Aniline and Aniline Hydrochloride. Drisko RW and McKennis Jr H.

J. Am. Chem. Soc. 74(10) , 2626-2628, (1952)

The Synthesis of Substituted β-Thienyl-and β-Furylglutaric Acids. Smith Jr WT and Shelton RW.

J. Am. Chem. Soc. 76(10) , 2731-2732, (1954)

Waterpipe smoke: a considerable source of human exposure against furanic compounds. Schubert J, et al.

Anal. Chim. Acta 709 , 105-112, (2012)

 Synonyms

5-Chloro-2-furaldehyde,stabilized
5-formyl-2-chlorofuran
2-Furancarboxaldehyde,5-chloro
2-chloro-5-formylfuran
MFCD02752599
5-Chloro-2-furaldehyde
5-chlorofurane-2-carbaldehyde
5-Chlorofurfural
2-Furancarboxaldehyde, 5-chloro-
5-chloro-2-furfural