Tamrintamab

Modify Date: 2024-04-10 14:25:06

Tamrintamab Structure
Tamrintamab structure
 Common Name Tamrintamab
CAS Number 2148325-59-9 Molecular Weight N/A
Density N/A Boiling Point N/A
Molecular Formula N/A Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Tamrintamab


Tamrintamab (SC-003 mAb, SC-Mab003, SC34.28ss1) is an ADC Antibody targeting to dipeptidase 3 (DPEP3 or MBD3). DPEP3 is a glycosyl phosphatidylinositol anchored metallopeptidase that is overexpressed in ovarian tumors. Tamrintamab can specifically bind DPEP3-expressing cells to produce cytotoxicity. Tamrintamab can be used in ovarian cancer research[1][2].

 Names

Name Tamrintamab

 Tamrintamab Biological Activity

Description Tamrintamab (SC-003 mAb, SC-Mab003, SC34.28ss1) is an ADC Antibody targeting to dipeptidase 3 (DPEP3 or MBD3). DPEP3 is a glycosyl phosphatidylinositol anchored metallopeptidase that is overexpressed in ovarian tumors. Tamrintamab can specifically bind DPEP3-expressing cells to produce cytotoxicity. Tamrintamab can be used in ovarian cancer research[1][2].
Related Catalog
In Vitro Tamrintamab is a monoclonal antibody targeting dipeptidase 3 (DPEP3 or MBD3) via a maleimide splice cleavable by protease[1].
References

[1]. Martín-Sabroso C, et al. Antibody-Antineoplastic Conjugates in Gynecological Malignancies: Current Status and Future Perspectives. Pharmaceutics. 2021 Oct 15;13(10):1705.  

[2]. Wiedemeyer W R, et al. Abstract NT-113: SC-003, AN ANTIBODY-DRUG CONJUGATE TARGETING DIPEPTIDASE 3, EXHIBITS POTENT ANTI-TUMOR ACTIVITY IN PATIENT-DERIVED XENOGRAFT MODELS OF HIGH GRADE SEROUS OVARIAN CANCER[J]. Clinical Cancer Research, 2019, 25(22_Supplement): NT-113-NT-113.

 Chemical & Physical Properties

No Any Chemical & Physical Properties
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Chemsrc provides Tamrintamab(CAS#:2148325-59-9) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of Tamrintamab are included as well.>> amp version: Tamrintamab

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