TGR5 agonist 3

Modify Date: 2024-01-17 16:42:43

Use of TGR5 agonist 3

TGR5 agonist 3 (compound 8), a Cholic acid derivative, is a selective TGR5 agonist with an EC50 of 5 μM[1].

Name	TGR5 agonist 3

Description	TGR5 agonist 3 (compound 8), a Cholic acid derivative, is a selective TGR5 agonist with an EC50 of 5 μM[1].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> GPCR19 Research Areas >> Inflammation/Immunology
References	[1]. Emiliano Rosatelli, et al. Chemical exploration of TGR5 functional hot-spots: Synthesis and structure-activity relationships of C7- and C23-Substituted cholic acid derivatives. Eur J Med Chem. 2023 Oct 1:261:115851.

Molecular Formula	C₂₈H₄₈O₅
Molecular Weight	464.68