GSK3004774

Modify Date: 2024-01-11 17:20:46

GSK3004774 Structure
GSK3004774 structure
Common Name GSK3004774
CAS Number 2138814-32-9 Molecular Weight 528.69
Density N/A Boiling Point N/A
Molecular Formula C32H40N4O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of GSK3004774


GSK3004774 is a potent, nonabsorbable agonist of CaSR, with an pEC50 of 7.3, 6.6 and 6.5 for human, mouse and rat CaSR, respectively. GSK3004774 shows an EC50 of 50 nM for human CaSR[1].

 Names

Name GSK3004774

 GSK3004774 Biological Activity

Description GSK3004774 is a potent, nonabsorbable agonist of CaSR, with an pEC50 of 7.3, 6.6 and 6.5 for human, mouse and rat CaSR, respectively. GSK3004774 shows an EC50 of 50 nM for human CaSR[1].
Related Catalog
References

[1]. Sparks SM, et al. Identification of potent, nonabsorbable agonists of the calcium-sensing receptor for GI-specific administration. Bioorg Med Chem Lett. 2017 Oct 15;27(20):4673-4677.

 Chemical & Physical Properties

Molecular Formula C32H40N4O3
Molecular Weight 528.69
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