Dirocaftor

Modify Date: 2025-08-22 14:50:56

Dirocaftor Structure
Dirocaftor structure
 Common Name Dirocaftor
CAS Number 2137932-23-9 Molecular Weight 424.64
Density N/A Boiling Point N/A
Molecular Formula C22H28N2O3Si2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Dirocaftor


Dirocaftor (PTI-808) is a CFTR potentiator that enhances the function of CFTR protein by opening chloride channels. Dirocaftor can be used for cystic fibrosis (CF) research[1][2].

 Names

Name Dirocaftor

 Dirocaftor Biological Activity

Description Dirocaftor (PTI-808) is a CFTR potentiator that enhances the function of CFTR protein by opening chloride channels. Dirocaftor can be used for cystic fibrosis (CF) research[1][2].
Related Catalog
In Vitro When combined with Nesolicaftor and Posenacaftor, Dirocaftor can restore CFTR function to nearly normal levels[2].
References

[1]. James A Reihill, et al. Modulation of Ion Transport to Restore Airway Hydration in Cystic Fibrosis. Genes (Basel). 2021 Mar 22;12(3):453.

[2]. P. van Mourik, et al. WS10 Moving beyond body mass index to assess nutritional status in CF. Journal of Cystic Fibrosis 19S2 (2020) S1-S36.

 Chemical & Physical Properties

Molecular Formula C22H28N2O3Si2
Molecular Weight 424.64
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Chemsrc provides Dirocaftor(CAS#:2137932-23-9) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of Dirocaftor are included as well.>> amp version: Dirocaftor

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