YW2065
YW2065 structure
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Common Name | YW2065 | ||
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| CAS Number | 2131223-85-1 | Molecular Weight | 407.271 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C20H15BrN4O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of YW2065YW2065 has excellent anti-colorectal cancer effects in vitro and in vivo. YW2065 achieves its inhibitory activity for Wnt signaling by stabilizing Axin-1, a scaffolding protein that regulates proteasome degradation of β-catenin. Simultaneously, YW2065 also led to the activation of the tumor suppressor AMPK, providing an additional anticancer mechanism. In addition, YW2065 showed favorable pharmacokinetic properties without obvious toxicity. |
| Name | YW2065 |
|---|
| Description | YW2065 has excellent anti-colorectal cancer effects in vitro and in vivo. YW2065 achieves its inhibitory activity for Wnt signaling by stabilizing Axin-1, a scaffolding protein that regulates proteasome degradation of β-catenin. Simultaneously, YW2065 also led to the activation of the tumor suppressor AMPK, providing an additional anticancer mechanism. In addition, YW2065 showed favorable pharmacokinetic properties without obvious toxicity. |
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| Molecular Formula | C20H15BrN4O |
|---|---|
| Molecular Weight | 407.271 |