AN11251

Modify Date: 2025-08-21 17:08:57

AN11251 Structure
AN11251 structure
Common Name AN11251
CAS Number 2130750-59-1 Molecular Weight 528.42
Density N/A Boiling Point N/A
Molecular Formula C29H38BFO7 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of AN11251


AN11251 is a potent and oral active anti-Wolbachia agent with potential for treatment of onchocerciasis and lymphatic filariasis, with EC50 values of 1.5 nM in LDW1 cell lines and 15 nM in C6/36 cell lines[1].

 Names

Name AN11251

 AN11251 Biological Activity

Description AN11251 is a potent and oral active anti-Wolbachia agent with potential for treatment of onchocerciasis and lymphatic filariasis, with EC50 values of 1.5 nM in LDW1 cell lines and 15 nM in C6/36 cell lines[1].
Related Catalog
References

[1]. Jacobs RT, et al. Boron-Pleuromutilins as Anti- Wolbachia Agents with Potential for Treatment of Onchocerciasis and Lymphatic Filariasis. J Med Chem. 2019 Mar 14;62(5):2521-2540.

 Chemical & Physical Properties

Molecular Formula C29H38BFO7
Molecular Weight 528.42
InChIKey WQVDRQUAJNEZSV-PTUZOVCBSA-N
SMILES C=CC1(C)CC(OC(=O)COc2ccc3c(c2F)B(O)OC3)C2(C)C(C)CCC3(CCC(=O)C32)C(C)C1O
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