AN11251

Names

[ Name ]:
AN11251

Biological Activity

[Description]:

AN11251 is a potent and oral active anti-Wolbachia agent with potential for treatment of onchocerciasis and lymphatic filariasis, with EC50 values of 1.5 nM in LDW1 cell lines and 15 nM in C6/36 cell lines[1].

[Related Catalog]:

Signaling Pathways >> Anti-infection >> Parasite

Research Areas >> Infection

[References]

[1]. Jacobs RT, et al. Boron-Pleuromutilins as Anti- Wolbachia Agents with Potential for Treatment of Onchocerciasis and Lymphatic Filariasis. J Med Chem. 2019 Mar 14;62(5):2521-2540.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₉H₃₈BFO₇

[ Molecular Weight ]:
528.42

Related Compounds

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