N-Dbco-N-bis(peg2-nhs ester)

Modify Date: 2024-01-08 20:13:06

N-Dbco-N-bis(peg2-nhs ester) Structure
N-Dbco-N-bis(peg2-nhs ester) structure
Common Name N-Dbco-N-bis(peg2-nhs ester)
CAS Number 2128735-29-3 Molecular Weight 818.82
Density N/A Boiling Point N/A
Molecular Formula C41H46N4O14 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of N-Dbco-N-bis(peg2-nhs ester)


N-DBCO-N-bis(PEG2-C2-NHS ester) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name N-DBCO-N-bis(PEG2-C2-NHS ester)
Synonym More Synonyms

 N-Dbco-N-bis(peg2-nhs ester) Biological Activity

Description N-DBCO-N-bis(PEG2-C2-NHS ester) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C41H46N4O14
Molecular Weight 818.82

 Synonyms

MFCD29912779
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