2128735-29-3

2128735-29-3 structure
2128735-29-3 structure
  • Name: N-Dbco-N-bis(peg2-nhs ester)
  • Chemical Name: N-DBCO-N-bis(PEG2-C2-NHS ester)
  • CAS Number: 2128735-29-3
  • Molecular Formula: C41H46N4O14
  • Molecular Weight: 818.82
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 14:08:32
  • Modify Date: 2024-01-08 20:13:06
  • N-DBCO-N-bis(PEG2-C2-NHS ester) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name N-DBCO-N-bis(PEG2-C2-NHS ester)
Synonyms MFCD29912779
Description N-DBCO-N-bis(PEG2-C2-NHS ester) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C41H46N4O14
Molecular Weight 818.82