Shield-1 analog

Modify Date: 2025-11-27 07:16:20

Shield-1 analog Structure
Shield-1 analog structure
Common Name Shield-1 analog
CAS Number 2127390-15-0 Molecular Weight 678.81
Density N/A Boiling Point N/A
Molecular Formula C38H50N2O9 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Shield-1 analog


AP1867-3-(Methoxyethylamine), the AP1867 based moiety, is a synthetic ligand for FKBP. AP1867-3-(Methoxyethylamine) can be used in the synthesis of PROTAC FKBP12 F36V degrader[1].

 Names

Name AP1867-3-(Methoxyethylamine)

 Shield-1 analog Biological Activity

Description AP1867-3-(Methoxyethylamine), the AP1867 based moiety, is a synthetic ligand for FKBP. AP1867-3-(Methoxyethylamine) can be used in the synthesis of PROTAC FKBP12 F36V degrader[1].
Related Catalog
References

[1]. Ottis P, et al. Assessing Different E3 Ligases for Small Molecule Induced Protein Ubiquitination and Degradation. ACS Chem Biol. 2017 Oct 20;12(10):2570-2578.

 Chemical & Physical Properties

Molecular Formula C38H50N2O9
Molecular Weight 678.81
InChIKey IUXMLUSGUQVKAO-RWSKJCERSA-N
SMILES CCC(C(=O)N1CCCCC1C(=O)OC(CCc1ccc(OC)c(OC)c1)c1cccc(OCCN)c1)c1cc(OC)c(OC)c(OC)c1
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